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Breakthrough in EB research

The Butterfly Children Charity-DEBRA are very excited to share the results of a skin graft trial, published yesterday in the science journal Nature and shared by many sources of media nationally and internationally.The study focused on grafting the skin of a 7 year old boy with junctional Epidermolysis bullosa.

A small piece of his skin was genetically modified to contain the correct gene. The corrected skin cells were then grown into skin grafts which were transplanted to cover 80% of the child’s body. In the year following the transplant, the skin remains robust and did not suffer from blistering.

The researchers have attributed the success to stem cells called holoclones that can extensively self-renew.

What is the next stage?

These results demonstrate a major advance in the research of treatments for the condition. However it is important that we contain our excitement as it is necessary to wait for further results in order to know whether the therapy can help others affected by junctional Epidermolysis bullosa as well as other types of Epidermolysis bullosa.

The Butterfly Children Charity-DEBRA is a founding member of the worldwide network, DEBRA INTERNATIONAL.

Through this network the results of all international research studies are shared therefore we will keep you informed of any relevant progress.

If you have any questions please call us at 952 816 434 or write to us at If you would like to read the full report please click here


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